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Potential environmentally-driven alterations in certain epigenetic marks — DNA modifications that control gene activity — were detected in the blood of people with newly diagnosed, treatment-naïve, sporadic Parkinson’s disease, a [...]
A dozen years after its first meeting, the International Linked Clinical Trials (iLCT) program is continuing to expand upon its ongoing efforts to ultimately heighten the number of treatment options in [...]
A test known as the alpha-synuclein seed amplification assay, or alphaSyn-SAA, was able to measure the accumulation of alpha-synuclein protein in the blood up to 10 years before a clinical [...]
A six-week Pilates-based exercise program helped reduce bradykinesia of the upper limbs in a small group of people with Parkinson’s disease, a study from Brazil reports. The study, “Short-term effects [...]
Variations in genes that are important for the function of lysosomes — the cellular equivalent of garbage disposals, which are responsible for removing molecular waste from cells — may help [...]
Researchers have developed analogs of cannabinol (CBN), a lesser-known cannabinoid, that show neuroprotective abilities in lab studies not unlike the effects from the active chemicals in the cannabis plant, which [...]
Researchers in Canada have developed a new method to generate functional dopaminergic neurons, the dopamine-producing nerve cells lost in Parkinson’s disease, from human pluripotent stem cells (hPSC). The scientists used [...]
Researchers have found a way to better control the preclinical generation of key neurons depleted in Parkinson's disease, pointing toward a new approach for a disease with no cure and [...]
A new study found certain genetic variants could help explain how long-term pesticide exposure could increase the risk of Parkinson's disease. [...]
Although there are still some aspects pending confirmation for its use in the clinical setting, and its resolution needs to be improved slightly, a study has shown that a method [...]
Researchers have used artificial intelligence techniques to massively accelerate the search for Parkinson's disease treatments. The researchers designed and used an AI-based strategy to identify compounds that block the clumping, [...]
A new study offers a first look into the complex molecular changes that occur in brain cells with Lewy bodies, which are key pathological hallmarks of Parkinson's disease and some [...]
New hypothesis paper builds on a growing scientific consensus that Parkinson's disease route to the brain starts in either the nose or the gut and proposes that environmental toxicants are [...]
Lewy body disease may be more common in middle-aged people than previously thought, according to a recent study. In the study, almost one in ten of over 50-year-olds were found [...]